Role of Janus-Kinases in Major Depressive Disorder

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Role of Janus-Kinases in Major Depressive Disorder.

BACKGROUND/AIMS Major depressive disorder is a severe, common and often chronic disease with a significant mortality due to suicide. The pathogenesis of major depression is still unknown. It is assumed that a reduction of neurogenesis in the hippocampus plays an important role in the development of major depressive disorder. However, the mechanisms that control proliferation of neuronal stem ce...

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ژورنال

عنوان ژورنال: Neurosignals

سال: 2016

ISSN: 1424-862X,1424-8638

DOI: 10.1159/000442613